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This orthogroup contains 194 genes from 131 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 194 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR19290 | BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED | 170 / 194 | 87.6% | 97.7% of 174 | ≥80% support |
| Pfam | PF00010 | HLH — Helix-loop-helix DNA-binding domain | 173 / 194 | 89.2% | 99.4% of 174 | ≥80% support |
| GO | GO:0046983 Molecular Function | protein dimerization activity | 174 / 194 | 89.7% | 100.0% of 174 | ≥80% support |
| GO | GO:0000981 Molecular Function | DNA-binding transcription factor activity, RNA polymerase II-specific | 172 / 194 | 88.7% | 98.9% of 174 | ≥80% support |
| GO | GO:0005634 Cellular Component | nucleus | 133 / 194 | 68.6% | 76.4% of 174 | ≥50% support |
| GO | GO:0003700 Molecular Function | DNA-binding transcription factor activity | 130 / 194 | 67.0% | 74.7% of 174 | ≥50% support |
| GO | GO:0007423 Biological Process | sensory organ development | 130 / 194 | 67.0% | 74.7% of 174 | ≥50% support |
| GO | GO:0045944 Biological Process | positive regulation of transcription by RNA polymerase II | 130 / 194 | 67.0% | 74.7% of 174 | ≥50% support |
| GO | GO:0061564 Biological Process | axon development | 130 / 194 | 67.0% | 74.7% of 174 | ≥50% support |
| GO | GO:0070888 Molecular Function | E-box binding | 130 / 194 | 67.0% | 74.7% of 174 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Acropora acuminata | aacu_s0188.g4.t1 | XP_015764033.1 | PREDICTED: neurogenic differentiation factor 1-like [Acropora digitifera] | O42202 Neurogenic differentiation factor 1 OS=Danio rerio OX=7955 G | JBrowse |
| Alatina alata | Aala_g1251.t1 | XP_020628081.1 | uncharacterized protein LOC110065298 [Orbicella faveolata] | P46531 Neurogenic locus notch homolog protein 1 OS=Homo sapiens OX= | JBrowse |
| Alatina alata | Aala_g1517.t1 | CAH3037199.1 | unnamed protein product, partial [Porites lobata] | P46581 Neurogenic differentiation factor 1 OS=Caenorhabditis elegan | JBrowse |
| Alatina alata | Aala_g1558.t1 | EDO36268.1 | predicted protein, partial [Nematostella vectensis] | O95789 Zinc finger MYM-type protein 6 OS=Homo sapiens OX=9606 GN=ZM | JBrowse |
| Alatina alata | Aala_g1559.t1 | XP_032232313.1 | class E basic helix-loop-helix protein 22 isoform X2 [Nematostella vectensis] | P79766 Neurogenic differentiation factor 4 OS=Gallus gallus OX=9031 | JBrowse |
| Alatina alata | Aala_g1560.t1 | XP_020896568.1 | neurogenic differentiation factor 1 [Exaiptasia diaphana] | P18067 Ras-related protein Rab-7a OS=Canis lupus familiaris OX=9615 | JBrowse |
| Alatina alata | Aala_g1659.t1 | MCP3853013.1 | hypothetical protein [Gammaproteobacteria bacterium] | O02751 Craniofacial development protein 2 OS=Bos taurus OX=9913 GN= | JBrowse |
| Alatina alata | Aala_g1977.t1 | KAI4463942.1 | transposable element-related [Holotrichia oblita] | Q9P225 Dynein axonemal heavy chain 2 OS=Homo sapiens OX=9606 GN=DNA | JBrowse |
| Alatina alata | Aala_g205.t1 | MCP5002498.1 | hypothetical protein [Planctomycetota bacterium] | Q9QZA6 CD151 antigen OS=Rattus norvegicus OX=10116 GN=Cd151 PE=1 SV | JBrowse |
| Alatina alata | Aala_g2351.t1 | XP_052081199.1 | piggyBac transposable element-derived protein 5-like [Mytilus californianus] | Q6F2E4 Forkhead box protein D1 OS=Xenopus tropicalis OX=8364 GN=fox | JBrowse |
| Alatina alata | Aala_g2564.t1 | ALJ33560.1 | Hlh-6, partial [Clytia hemisphaerica] | A1Z713 Intermembrane lipid transfer protein Vps13 OS=Drosophila mel | JBrowse |
| Alatina alata | Aala_g2566.t1 | XP_031563904.1 | neurogenic differentiation factor 6-B-like [Actinia tenebrosa] | P46581 Neurogenic differentiation factor 1 OS=Caenorhabditis elegan | JBrowse |
| Alatina alata | Aala_g2628.t1 | XP_032232313.1 | class E basic helix-loop-helix protein 22 isoform X2 [Nematostella vectensis] | P46581 Neurogenic differentiation factor 1 OS=Caenorhabditis elegan | JBrowse |
| Alatina alata | Aala_g2659.t1 | KAI8486591.1 | hypothetical protein Bbelb_355660 [Branchiostoma belcheri] | Q5SSH7 Zinc finger ZZ-type and EF-hand domain-containing protein 1 | JBrowse |
| Alatina alata | Aala_g294.t1 | XP_020608888.1 | monocarboxylate transporter 10-like [Orbicella faveolata] | O35440 Monocarboxylate transporter 2 OS=Meriones unguiculatus OX=10 | JBrowse |
| Alatina alata | Aala_g366.t1 | CAH3029636.1 | unnamed protein product [Porites evermanni] | Q64285 Bile salt-activated lipase OS=Mus musculus OX=10090 GN=Cel P | JBrowse |
| Alatina alata | Aala_g399.t1 | CAD7412218.1 | unnamed protein product, partial [Timema cristinae] | E9Q236 ATP-binding cassette sub-family C member 4 OS=Mus musculus O | JBrowse |
| Aurelia aurita | scaffold113.g14.t1 | none | – | JBrowse | |
| Acropora austera | ENSKKQP00000039890.1 | XP_015764033.1 | PREDICTED: neurogenic differentiation factor 1-like [Acropora digitifera] | O42202 Neurogenic differentiation factor 1 OS=Danio rerio OX=7955 G | JBrowse |
| Acropora awi | aawi_s0123.g13.t1 | XP_015764033.1 | PREDICTED: neurogenic differentiation factor 1-like [Acropora digitifera] | O42202 Neurogenic differentiation factor 1 OS=Danio rerio OX=7955 G | JBrowse |
