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This orthogroup contains 461 genes from 111 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 461 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR14074 | HELICASE WITH DEATH DOMAIN-RELATED | 408 / 461 | 88.5% | 99.8% of 409 | ≥80% support |
| Pfam | PF18119 | RIG-I_C — RIG-I receptor C-terminal domain | 376 / 461 | 81.6% | 89.5% of 420 | ≥80% support |
| Pfam | PF00271 | Helicase_C — Helicase conserved C-terminal domain | 373 / 461 | 80.9% | 88.8% of 420 | ≥80% support |
| Pfam | PF11648 | RIG-I_C-RD — C-terminal domain of RIG-I | 372 / 461 | 80.7% | 88.6% of 420 | ≥80% support |
| GO | GO:0005737 Cellular Component | cytoplasm | 408 / 461 | 88.5% | 100.0% of 408 | ≥80% support |
| Pfam | PF16739 | CARD_2 — Caspase recruitment domain | 282 / 461 | 61.2% | 67.1% of 420 | ≥50% support |
| Pfam | PF04851 | ResIII — Type III restriction enzyme, res subunit | 244 / 461 | 52.9% | 58.1% of 420 | ≥50% support |
| GO | GO:0005524 Molecular Function | ATP binding | 367 / 461 | 79.6% | 90.0% of 408 | ≥50% support |
| GO | GO:0003677 Molecular Function | DNA binding | 244 / 461 | 52.9% | 59.8% of 408 | ≥50% support |
| GO | GO:0016787 Molecular Function | hydrolase activity | 244 / 461 | 52.9% | 59.8% of 408 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Leptogorgia sarmentosa | ENSAPQP00000030080.1 | CAB3983752.1 | probable ATP-dependent RNA helicase DDX58 [Paramuricea clavata] | Q6Q899 Antiviral innate immune response receptor RIG-I OS=Mus muscu | JBrowse |
| Leptogorgia sarmentosa | ENSAPQP00000030085.1 | CAB4007921.1 | probable ATP-dependent RNA helicase DDX58 [Paramuricea clavata] | Q6Q899 Antiviral innate immune response receptor RIG-I OS=Mus muscu | JBrowse |
| Leptogorgia sarmentosa | ENSAPQP00000030106.1 | CAB4007921.1 | probable ATP-dependent RNA helicase DDX58 [Paramuricea clavata] | Q6Q899 Antiviral innate immune response receptor RIG-I OS=Mus muscu | JBrowse |
