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This orthogroup contains 238 genes from 140 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 238 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR10340 | SPHINGOMYELIN PHOSPHODIESTERASE | 201 / 238 | 84.5% | 99.5% of 202 | ≥80% support |
| GO | GO:0005615 Cellular Component | extracellular space | 201 / 238 | 84.5% | 99.0% of 203 | ≥80% support |
| GO | GO:0008081 Molecular Function | phosphoric diester hydrolase activity | 201 / 238 | 84.5% | 99.0% of 203 | ≥80% support |
| Pfam | PF00149 | Metallophos — Calcineurin-like phosphoesterase | 181 / 238 | 76.1% | 91.4% of 198 | ≥50% support |
| Pfam | PF19272 | ASMase_C — Acid sphingomyelin phosphodiesterase C-terminal region | 163 / 238 | 68.5% | 82.3% of 198 | ≥50% support |
| GO | GO:0016787 Molecular Function | hydrolase activity | 181 / 238 | 76.1% | 89.2% of 203 | ≥50% support |
| GO | GO:0006685 Biological Process | sphingomyelin catabolic process | 142 / 238 | 59.7% | 70.0% of 203 | ≥50% support |
| GO | GO:0004767 Molecular Function | sphingomyelin phosphodiesterase activity | 137 / 238 | 57.6% | 67.5% of 203 | ≥50% support |
| KEGG | K12350 | SMPD1, ASM — Necroptosis | 145 / 238 | 60.9% | 91.2% of 159 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Paragorgia papillata | Ppa0G207460 | CAB3983954.1 | sphingomyelin phosphodiesterase-like [Paramuricea clavata] | Q0VD19 Sphingomyelin phosphodiesterase OS=Bos taurus OX=9913 GN=SMP | JBrowse |
| Paragorgia papillata | Ppa0G207470 | CAB3983955.1 | sphingomyelin phosphodiesterase isoform X1 [Paramuricea clavata] | Q0VD19 Sphingomyelin phosphodiesterase OS=Bos taurus OX=9913 GN=SMP | JBrowse |
