Genomic Location: LJWW01000114.1:258727...272122
NR annotation: KXJ20343.1, Spectrin alpha chain, non-erythrocytic 1 [Exaiptasia diaphana]
Species Exaiptasia diaphana · all data for this species · gene families
| CDS |
| KXJ20343.1 |
| Protein |
| KXJ20343.1 |
| UniProt accession | Description |
|---|---|
| Q13813 | Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3 |
| P16086 | Spectrin alpha chain, non-erythrocytic 1 OS=Rattus norvegicus OX=10116 GN=Sptan1 PE=1 SV=2 |
| P16546 | Spectrin alpha chain, non-erythrocytic 1 OS=Mus musculus OX=10090 GN=Sptan1 PE=1 SV=4 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0001340 (this species only) · gene tree & orthology |
| Ubiquitin family | UBD|Other|SH3 · all ubiquitin genes in this species |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00036 all species → | EF-hand_1 | EF hand | Domain | Interproscan |
| PF00018 all species → | SH3_1 | SH3 domain | Domain | Interproscan |
| PF00435 all species → | Spectrin | Spectrin repeat | Domain | Interproscan |
| PF08726 all species → | EFhand_Ca_insen | Ca2+ insensitive EF hand | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR011992 all species → | Homologous_superfamily | EF-hand domain pair | Interproscan |
| IPR002048 all species → | Domain | EF-hand domain | Interproscan |
| IPR001452 all species → | Domain | SH3 domain | Interproscan |
| IPR036028 all species → | Homologous_superfamily | SH3-like domain superfamily | Interproscan |
| IPR018247 all species → | Binding_site | EF-Hand 1, calcium-binding site | Interproscan |
| IPR018159 all species → | Repeat | Spectrin/alpha-actinin | Interproscan |
| IPR002017 all species → | Repeat | Spectrin repeat | Interproscan |
| IPR014837 all species → | Domain | EF-hand, Ca insensitive | Interproscan |
| IPR035825 all species → | Domain | Alpha Spectrin, SH3 domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR11915 all species → | SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0005509 all species → | Molecular Function | calcium ion binding | Interproscan |
| GO:0005515 all species → | Molecular Function | protein binding | Interproscan |
| GO:0005886 all species → | Cellular Component | plasma membrane | Interproscan |
| GO:0030036 all species → | Biological Process | actin cytoskeleton organization | Interproscan |
| GO:0030054 all species → | Cellular Component | cell junction | Interproscan |
| GO:0030864 all species → | Cellular Component | cortical actin cytoskeleton | Interproscan |
| GO:0042995 all species → | Cellular Component | cell projection | Interproscan |
| GO:0051015 all species → | Molecular Function | actin filament binding | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K06114 | SPTAN; spectrin alpha, non-erythrocytic (fodrin) | - | Cytoskeleton proteins | ko04812 | deepkoala |
Transcript abundance of KXJ20343.1 across 72 RNA-seq samples of Exaiptasia diaphana. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| whole animal · aposymbiotic | 36 | 36 | 184.77 | 268.34 | |
| whole animal · symbiotic | 36 | 36 | 254.91 | 385.24 |
| SRA run | Condition | Tissue | Developmental stage | Treatment | Study | TPM |
|---|---|---|---|---|---|---|
| SRR6202345 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 268.34 |
| SRR6202260 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 262.98 |
| SRR6202344 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 262.58 |
| SRR6202241 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 262.03 |
| SRR6202233 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 260.00 |
| SRR6202261 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 255.16 |
| SRR6202234 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 253.68 |
| SRR6202242 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 249.94 |
| SRR6202258 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 249.84 |
| SRR6202364 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 247.57 |
| SRR6202259 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 246.95 |
| SRR6202346 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 242.56 |
| SRR6202343 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 213.98 |
| SRR6202358 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 204.71 |
| SRR6202211 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 198.20 |
| SRR6202212 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 194.27 |
| SRR6202209 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 191.71 |
| SRR6202210 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 187.01 |
| SRR6202363 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 181.75 |
| SRR6202206 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 179.75 |
| SRR6202208 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 178.15 |
| SRR6202207 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 177.32 |
| SRR6202205 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 177.31 |
| SRR6202357 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 159.35 |
| SRR6202236 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 150.10 |
| SRR6202238 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 142.00 |
| SRR6202237 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 140.88 |
| SRR6202254 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 138.90 |
| SRR6202235 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 137.77 |
| SRR6202255 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 133.42 |
| SRR6202239 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 91.72 |
| SRR6202240 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 85.14 |
| SRR6202204 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 84.01 |
| SRR6202203 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 83.29 |
| SRR6202256 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 81.70 |
| SRR6202257 | whole animal · aposymbiotic | whole animal | not recorded | aposymbiotic | SRP120942 | 77.72 |
| SRR6202304 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 385.24 |
| SRR6202305 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 384.30 |
| SRR6202284 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 380.38 |
| SRR6202303 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 379.72 |
| SRR6202285 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 374.89 |
| SRR6202306 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 373.24 |
| SRR6202309 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 275.90 |
| SRR6202282 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 268.42 |
| SRR6202307 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 267.77 |
| SRR6202340 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 264.03 |
| SRR6202310 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 263.26 |
| SRR6202262 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 259.69 |
| SRR6202283 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 259.43 |
| SRR6202263 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 259.15 |
| SRR6202341 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 258.94 |
| SRR6202339 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 258.79 |
| SRR6202342 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 257.30 |
| SRR6202308 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 254.09 |
| SRR6202354 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 247.25 |
| SRR6202353 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 234.10 |
| SRR6202277 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 218.90 |
| SRR6202337 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 218.19 |
| SRR6202349 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 216.10 |
| SRR6202356 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 214.14 |
| SRR6202338 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 213.93 |
| SRR6202276 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 213.35 |
| SRR6202281 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 208.14 |
| SRR6202352 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 205.31 |
| SRR6202350 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 205.08 |
| SRR6202347 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 199.75 |
| SRR6202280 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 199.16 |
| SRR6202279 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 196.35 |
| SRR6202355 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 193.76 |
| SRR6202278 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 192.38 |
| SRR6202351 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 191.16 |
| SRR6202348 | whole animal · symbiotic | whole animal | not recorded | symbiotic | SRP120942 | 185.09 |
Source: CnidoSite RNA-seq expression matrices (EDIAP_TPM,
StringTie quantification over 72 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
Peptides from this gene's protein product were identified in 2 re-processed proteomic datasets at a false discovery rate of q ≤ 0.01 (Comet + Percolator).
| Dataset | Species | Tissue / condition | Peptides | PSMs | Coverage | Best q | |
|---|---|---|---|---|---|---|---|
| PXD055908 | Exaiptasia diaphana | Whole anemone Heat stress (32℃) vs Control |
8 | 162 |
3%
|
0.0000707064 | peptides |
|
R.YEPVGNIDGLFVNNVR.K q=0.0000707064
R.LVWIESPVLPR.R q=0.00013678 R.EETSTVEEDDSDNSTLTKK.I q=0.000192666 R.WAEELASADSLTYSHER.G q=0.000343899 R.NTVEPVLFESDVK.Y q=0.000343899 R.LAIESQNFAEK.L q=0.00105258 K.NVDHIFEFIPR.N q=0.00172585 K.VTQIWYEEAK.H q=0.00844067 | |||||||
| PXD045585 | Exaiptasia diaphana | Symbiont Breviolum minutum Symbiosis establishment |
1 | 3 |
0.4%
|
0.00211379 | peptides |
|
R.NEPVDTGLLEEESIK.T q=0.00211379
| |||||||
Search parameters for this evidence: Comet 2026.01,
precursor 10 ppm, fragment 0.5 Da,
fixed C+57.021464, variable M+15.9949,n+42.010565,
PSM-level q ≤ 0.01 against
.
Parameters differ between datasets; open a dataset for its full provenance.
·
all proteins for Exaiptasia diaphana
Genes whose expression across the transcriptome samples of Exaiptasia diaphana tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
| Direction | Partners | Most correlated partner | PCC |
|---|---|---|---|
| Positively correlated | 42 | KXJ30221.1 | 0.974086807492417 |
| Negatively correlated | 43 | KXJ12241.1 | -0.915765992384613 |
Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.
Whether this gene can be visualised in the single-cell atlases of Exaiptasia diaphana, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
| Assay | Sample | Peaks | Region |
|---|
No called peak overlaps this gene in 2 available assays. Either the gene is not near an accessible or marked region in those samples, or it is not represented in the peak caller’s annotation.
Browse the full epigenomic landscape of this species: ChIP-seq · ATAC-seq.
| Sample | Methylation profile |
|---|---|
| whole_animal_aposymbiotic_1 | open |
| whole_animal_aposymbiotic_2 | open |
| whole_animal_aposymbiotic_3 | open |
| whole_animal_aposymbiotic_4 | open |
| whole_animal_aposymbiotic_5 | open |
| whole_animal_aposymbiotic_6 | open |
| whole_animal_aposymbiotic_7 | open |
| whole_animal_aposymbiotic_8 | open |
| whole_animal_aposymbiotic_9 | open |
| whole_animal_symbiotic_1 | open |
| whole_animal_symbiotic_10 | open |
| whole_animal_symbiotic_11 | open |
| whole_animal_symbiotic_12 | open |
| whole_animal_symbiotic_13 | open |
| whole_animal_symbiotic_14 | open |
| whole_animal_symbiotic_2 | open |
| whole_animal_symbiotic_3 | open |
| whole_animal_symbiotic_4 | open |
| whole_animal_symbiotic_5 | open |
| whole_animal_symbiotic_6 | open |
| whole_animal_symbiotic_7 | open |
| whole_animal_symbiotic_8 | open |
| whole_animal_symbiotic_9 | open |
The DNA Methylation page locates this gene by scanning the bisulphite table, which holds one row per cytosine. For the largest datasets that scan takes a while to return; it does not mean the link is broken.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | ready | open → |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |