Detailed information of KXJ27092.1 in Exaiptasia diaphana

Genomic Location: LJWW01000023.1:107174...137776
NR annotation: KXJ27092.1, Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 [Exaiptasia diaphana]
Species Exaiptasia diaphana · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
P0C6B8Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 OS=Rattus norvegicus OX=10116 GN=Svep1 PE=1 SV=1
A2AVA0Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 OS=Mus musculus OX=10090 GN=Svep1 PE=1 SV=1
Q4LDE5Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SVEP1 PE=1 SV=3
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0000607 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF00092
all species →
VWAvon Willebrand factor type A domainDomainInterproscan
PF00008
all species →
EGFEGF-like domainDomainInterproscan
PF14645
all species →
ChibbyChibby familyFamilyInterproscan
PF15711
all species →
ILEIInterleukin-like EMT inducerDomainInterproscan
PF00754
all species →
F5_F8_type_CF5/8 type C domainDomainInterproscan
PF00354
all species →
PentaxinPentaxin familyDomainInterproscan
PF00431
all species →
CUBCUB domainDomainInterproscan
PF00084
all species →
SushiSushi repeat (SCR repeat)DomainInterproscan
PF07699
all species →
Ephrin_rec_likeTyrosine-protein kinase ephrin type A/B receptor-like DomainInterproscan
PF12662
all species →
cEGFComplement Clr-like EGF-likeDomainInterproscan
PF02494
all species →
HYRHYR domainDomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR035976
all species →
Homologous_superfamilySushi/SCR/CCP superfamilyInterproscan
IPR000742
all species →
DomainEGF-like domainInterproscan
IPR002035
all species →
Domainvon Willebrand factor, type AInterproscan
IPR008979
all species →
Homologous_superfamilyGalactose-binding-like domain superfamilyInterproscan
IPR000436
all species →
DomainSushi/SCR/CCP domainInterproscan
IPR000421
all species →
DomainCoagulation factor 5/8 C-terminal domainInterproscan
IPR000859
all species →
DomainCUB domainInterproscan
IPR028118
all species →
FamilyChibby familyInterproscan
IPR039477
all species →
DomainILEI/PANDER domainInterproscan
IPR000152
all species →
PTMEGF-type aspartate/asparagine hydroxylation siteInterproscan
IPR036465
all species →
Homologous_superfamilyvon Willebrand factor A-like domain superfamilyInterproscan
IPR035914
all species →
Homologous_superfamilySpermadhesin, CUB domain superfamilyInterproscan
IPR001759
all species →
FamilyPentraxin-relatedInterproscan
IPR018097
all species →
Conserved_siteEGF-like calcium-binding, conserved siteInterproscan
IPR009030
all species →
Homologous_superfamilyGrowth factor receptor cysteine-rich domain superfamilyInterproscan
IPR001881
all species →
DomainEGF-like calcium-binding domainInterproscan
IPR003609
all species →
DomainPAN/Apple domainInterproscan
IPR003410
all species →
DomainHYR domainInterproscan
IPR003006
all species →
Conserved_siteImmunoglobulin/major histocompatibility complex, conserved siteInterproscan
IPR006558
all species →
DomainLamG-like jellyroll foldInterproscan
IPR013320
all species →
Homologous_superfamilyConcanavalin A-like lectin/glucanase domain superfamilyInterproscan
IPR011641
all species →
DomainTyrosine-protein kinase ephrin type A/B receptor-likeInterproscan
IPR026823
all species →
DomainComplement Clr-like EGF domainInterproscan
IPR050350
all species →
FamilyComplement & Cell Adhesion RegulatorsInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR19325
all species →
COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAININGInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0005509
all species →
Molecular Functioncalcium ion bindingInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
No KEGG orthology assignment for KXJ27092.1.

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of KXJ27092.1 across 72 RNA-seq samples of Exaiptasia diaphana. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

72Samples
67TPM > 0
2Conditions
42.2Max TPM
11.0Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
whole animal · aposymbiotic 36 32 5.92 11.83
whole animal · symbiotic 36 35 16.02 42.24

Per sample · hover a bar for the full sample record

Show the sample table (72 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
SRR6202234 whole animal · aposymbiotic whole animal not recorded aposymbiotic SRP120942 11.83
SRR6202242 whole animal · aposymbiotic whole animal not recorded aposymbiotic SRP120942 11.19
SRR6202261 whole animal · aposymbiotic whole animal not recorded aposymbiotic SRP120942 10.98
SRR6202260 whole animal · aposymbiotic whole animal not recorded aposymbiotic SRP120942 10.69
SRR6202241 whole animal · aposymbiotic whole animal not recorded aposymbiotic SRP120942 10.68
SRR6202233 whole animal · aposymbiotic whole animal not recorded aposymbiotic SRP120942 8.52
SRR6202358 whole animal · aposymbiotic whole animal not recorded aposymbiotic SRP120942 7.68
SRR6202204 whole animal · aposymbiotic whole animal not recorded aposymbiotic SRP120942 7.49
SRR6202344 whole animal · aposymbiotic whole animal not recorded aposymbiotic SRP120942 7.45
SRR6202203 whole animal · aposymbiotic whole animal not recorded aposymbiotic SRP120942 7.19
SRR6202239 whole animal · aposymbiotic whole animal not recorded aposymbiotic SRP120942 7.17
SRR6202240 whole animal · aposymbiotic whole animal not recorded aposymbiotic SRP120942 6.86
SRR6202346 whole animal · aposymbiotic whole animal not recorded aposymbiotic SRP120942 6.50
SRR6202259 whole animal · aposymbiotic whole animal not recorded aposymbiotic SRP120942 6.37
SRR6202205 whole animal · aposymbiotic whole animal not recorded aposymbiotic SRP120942 6.18
SRR6202257 whole animal · aposymbiotic whole animal not recorded aposymbiotic SRP120942 6.10
SRR6202211 whole animal · aposymbiotic whole animal not recorded aposymbiotic SRP120942 6.03
SRR6202256 whole animal · aposymbiotic whole animal not recorded aposymbiotic SRP120942 5.84
SRR6202258 whole animal · aposymbiotic whole animal not recorded aposymbiotic SRP120942 5.43
SRR6202208 whole animal · aposymbiotic whole animal not recorded aposymbiotic SRP120942 5.36
SRR6202255 whole animal · aposymbiotic whole animal not recorded aposymbiotic SRP120942 5.35
SRR6202206 whole animal · aposymbiotic whole animal not recorded aposymbiotic SRP120942 5.29
SRR6202236 whole animal · aposymbiotic whole animal not recorded aposymbiotic SRP120942 5.22
SRR6202209 whole animal · aposymbiotic whole animal not recorded aposymbiotic SRP120942 5.04
SRR6202237 whole animal · aposymbiotic whole animal not recorded aposymbiotic SRP120942 4.94
SRR6202210 whole animal · aposymbiotic whole animal not recorded aposymbiotic SRP120942 4.92
SRR6202212 whole animal · aposymbiotic whole animal not recorded aposymbiotic SRP120942 4.72
SRR6202363 whole animal · aposymbiotic whole animal not recorded aposymbiotic SRP120942 4.63
SRR6202207 whole animal · aposymbiotic whole animal not recorded aposymbiotic SRP120942 4.61
SRR6202235 whole animal · aposymbiotic whole animal not recorded aposymbiotic SRP120942 4.60
SRR6202238 whole animal · aposymbiotic whole animal not recorded aposymbiotic SRP120942 4.56
SRR6202254 whole animal · aposymbiotic whole animal not recorded aposymbiotic SRP120942 3.84
SRR6202343 whole animal · aposymbiotic whole animal not recorded aposymbiotic SRP120942 0.00
SRR6202345 whole animal · aposymbiotic whole animal not recorded aposymbiotic SRP120942 0.00
SRR6202357 whole animal · aposymbiotic whole animal not recorded aposymbiotic SRP120942 0.00
SRR6202364 whole animal · aposymbiotic whole animal not recorded aposymbiotic SRP120942 0.00
SRR6202354 whole animal · symbiotic whole animal not recorded symbiotic SRP120942 42.24
SRR6202342 whole animal · symbiotic whole animal not recorded symbiotic SRP120942 40.70
SRR6202339 whole animal · symbiotic whole animal not recorded symbiotic SRP120942 30.07
SRR6202262 whole animal · symbiotic whole animal not recorded symbiotic SRP120942 29.79
SRR6202263 whole animal · symbiotic whole animal not recorded symbiotic SRP120942 28.76
SRR6202341 whole animal · symbiotic whole animal not recorded symbiotic SRP120942 28.13
SRR6202348 whole animal · symbiotic whole animal not recorded symbiotic SRP120942 26.87
SRR6202340 whole animal · symbiotic whole animal not recorded symbiotic SRP120942 26.71
SRR6202276 whole animal · symbiotic whole animal not recorded symbiotic SRP120942 22.10
SRR6202337 whole animal · symbiotic whole animal not recorded symbiotic SRP120942 21.63
SRR6202277 whole animal · symbiotic whole animal not recorded symbiotic SRP120942 20.87
SRR6202338 whole animal · symbiotic whole animal not recorded symbiotic SRP120942 20.85
SRR6202353 whole animal · symbiotic whole animal not recorded symbiotic SRP120942 17.69
SRR6202352 whole animal · symbiotic whole animal not recorded symbiotic SRP120942 14.48
SRR6202280 whole animal · symbiotic whole animal not recorded symbiotic SRP120942 14.06
SRR6202356 whole animal · symbiotic whole animal not recorded symbiotic SRP120942 13.74
SRR6202281 whole animal · symbiotic whole animal not recorded symbiotic SRP120942 13.71
SRR6202351 whole animal · symbiotic whole animal not recorded symbiotic SRP120942 13.15
SRR6202347 whole animal · symbiotic whole animal not recorded symbiotic SRP120942 13.11
SRR6202278 whole animal · symbiotic whole animal not recorded symbiotic SRP120942 11.99
SRR6202355 whole animal · symbiotic whole animal not recorded symbiotic SRP120942 11.10
SRR6202350 whole animal · symbiotic whole animal not recorded symbiotic SRP120942 10.29
SRR6202279 whole animal · symbiotic whole animal not recorded symbiotic SRP120942 10.14
SRR6202307 whole animal · symbiotic whole animal not recorded symbiotic SRP120942 9.95
SRR6202308 whole animal · symbiotic whole animal not recorded symbiotic SRP120942 9.36
SRR6202310 whole animal · symbiotic whole animal not recorded symbiotic SRP120942 9.00
SRR6202309 whole animal · symbiotic whole animal not recorded symbiotic SRP120942 8.70
SRR6202283 whole animal · symbiotic whole animal not recorded symbiotic SRP120942 8.14
SRR6202282 whole animal · symbiotic whole animal not recorded symbiotic SRP120942 8.01
SRR6202304 whole animal · symbiotic whole animal not recorded symbiotic SRP120942 7.44
SRR6202305 whole animal · symbiotic whole animal not recorded symbiotic SRP120942 7.19
SRR6202303 whole animal · symbiotic whole animal not recorded symbiotic SRP120942 6.97
SRR6202306 whole animal · symbiotic whole animal not recorded symbiotic SRP120942 6.87
SRR6202284 whole animal · symbiotic whole animal not recorded symbiotic SRP120942 6.60
SRR6202285 whole animal · symbiotic whole animal not recorded symbiotic SRP120942 6.45
SRR6202349 whole animal · symbiotic whole animal not recorded symbiotic SRP120942 0.00

Source: CnidoSite RNA-seq expression matrices (EDIAP_TPM, StringTie quantification over 72 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Proteomic evidence

Peptides from this gene's protein product were identified in 2 re-processed proteomic datasets at a false discovery rate of q ≤ 0.01 (Comet + Percolator).

7Unique peptides
49PSMs
13.0%Max coverage
0.0001Best q-value
2Datasets
Dataset Species Tissue / condition Peptides PSMs Coverage Best q
PXD045587 Exaiptasia diaphana Symbiont Durusdinium trenchii
Symbiosis establishment
4 14
13%
0.000506757 peptides
K.MIAVALEQMIASSSLGNK.E q=0.000506757
K.LWADAYPSIEGLVQK.D q=0.000506757
K.ILEQEADISNMENR.N q=0.000851547
K.SYPDEFVTSPLSSGIR.E q=0.00101112
PXD045585 Exaiptasia diaphana Symbiont Breviolum minutum
Symbiosis establishment
3 35
9.3%
0.000121477 peptides
K.LWADAYPSIEGLVQK.D q=0.000121477
K.ILEQEADISNMENR.N q=0.000121477
K.SYPDEFVTSPLSSGIR.E q=0.000231884

Search parameters for this evidence: Comet 2026.01, precursor 10 ppm, fragment 0.5 Da, fixed C+57.021464, variable M+15.9949, PSM-level q ≤ 0.01 against . Parameters differ between datasets; open a dataset for its full provenance.  ·  all proteins for Exaiptasia diaphana

Co-expression network

Genes whose expression across the transcriptome samples of Exaiptasia diaphana tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated36KXJ15396.10.932137273463615
Negatively correlated7KXJ20980.1-0.654587267109676

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Exaiptasia diaphana, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

Peak calls overlapping this gene

AssaySamplePeaksRegion
ATAC-seqMild_Stress_Aposym1Exon 1

Browse the full epigenomic landscape of this species: ChIP-seq · ATAC-seq.

DNA methylation (bisulphite samples)

SampleMethylation profile
whole_animal_aposymbiotic_1open
whole_animal_aposymbiotic_2open
whole_animal_aposymbiotic_3open
whole_animal_aposymbiotic_4open
whole_animal_aposymbiotic_5open
whole_animal_aposymbiotic_6open
whole_animal_aposymbiotic_7open
whole_animal_aposymbiotic_8open
whole_animal_aposymbiotic_9open
whole_animal_symbiotic_1open
whole_animal_symbiotic_10open
whole_animal_symbiotic_11open
whole_animal_symbiotic_12open
whole_animal_symbiotic_13open
whole_animal_symbiotic_14open
whole_animal_symbiotic_2open
whole_animal_symbiotic_3open
whole_animal_symbiotic_4open
whole_animal_symbiotic_5open
whole_animal_symbiotic_6open
whole_animal_symbiotic_7open
whole_animal_symbiotic_8open
whole_animal_symbiotic_9open

The DNA Methylation page locates this gene by scanning the bisulphite table, which holds one row per cytosine. For the largest datasets that scan takes a while to return; it does not mean the link is broken.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.readyopen →
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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