Gene Family

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Member genes
223
Species
144
Sequences
223
Best annotation support
81.6%

Consensus functional annotation

No term is shared by every member gene — the best-supported term below covers 81.6% of the 223 members.

Support counts the member genes carrying the term. % of genes is that count over all 223 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.

Source Term Name / description Support % of genes % annotated Consistency
PANTHERPTHR47965ASPARTYL PROTEASE-RELATED182 / 22381.6%99.5%
of 183
≥80% support
PfamPF00026Asp190 / 22385.2%100.0%
of 190
≥80% support
GOGO:0004190
Molecular Function
aspartic-type endopeptidase activity187 / 22383.9%99.5%
of 188
≥80% support
GOGO:0006508
Biological Process
proteolysis187 / 22383.9%99.5%
of 188
≥80% support
GOGO:0016020
Cellular Component
membrane184 / 22382.5%97.9%
of 188
≥80% support
GOGO:0005768
Cellular Component
endosome182 / 22381.6%96.8%
of 188
≥80% support
GOGO:0005802
Cellular Component
trans-Golgi network182 / 22381.6%96.8%
of 188
≥80% support
GOGO:0005886
Cellular Component
plasma membrane182 / 22381.6%96.8%
of 188
≥80% support
GOGO:0006509
Biological Process
membrane protein ectodomain proteolysis182 / 22381.6%96.8%
of 188
≥80% support
GOGO:0050435
Biological Process
amyloid-beta metabolic process182 / 22381.6%96.8%
of 188
≥80% support
KEGGK04521BACE1 — Peptidases and inhibitors158 / 22370.9%99.4%
of 159
≥50% support
📊 Total members in OG0006108: 223
Show: genes per page

Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.

Species Gene ID Top NCBI-NR hit
(accession)
Top NCBI-NR hit description
(source organism)
Top UniProt hit
(Swiss-Prot)
Genome browser
Acropora acuminataaacu_s0138.g21.t1XP_044180741.1beta-secretase 1-like [Acropora millepora]Q2HJ40
Beta-secretase 1 OS=Bos taurus OX=9913 GN=BACE1 PE=2 SV=1
JBrowse
Alatina alataAala_g324.t1CAH3015094.1unnamed protein product [Porites evermanni]O75746
Electrogenic aspartate/glutamate antiporter SLC25A12, mitoch
JBrowse
Aurelia auritascaffold3.g135.t1noneJBrowse
Acropora austeraENSKKQP00000034596.1XP_044180741.1beta-secretase 1-like [Acropora millepora]Q2HJ40
Beta-secretase 1 OS=Bos taurus OX=9913 GN=BACE1 PE=2 SV=1
JBrowse
Acropora austeraENSKKQP00000034607.1XP_044180741.1beta-secretase 1-like [Acropora millepora]Q2HJ40
Beta-secretase 1 OS=Bos taurus OX=9913 GN=BACE1 PE=2 SV=1
JBrowse
Acropora awiaawi_s0119.g75.t1XP_044180741.1beta-secretase 1-like [Acropora millepora]Q2HJ40
Beta-secretase 1 OS=Bos taurus OX=9913 GN=BACE1 PE=2 SV=1
JBrowse
Acropora cervicornisKAK2573732.1XP_044180741.1beta-secretase 1-like [Acropora millepora]Q2HJ40
Beta-secretase 1 OS=Bos taurus OX=9913 GN=BACE1 PE=2 SV=1
JBrowse
Acropora cythereaacyt_s0244.g27.t1XP_044180741.1beta-secretase 1-like [Acropora millepora]Q2HJ40
Beta-secretase 1 OS=Bos taurus OX=9913 GN=BACE1 PE=2 SV=1
JBrowse
Acropora digitiferachr1Alt.g2232.t1noneJBrowse
Acropora echinataaech_s0002.g232.t1XP_044180741.1beta-secretase 1-like [Acropora millepora]Q2HJ40
Beta-secretase 1 OS=Bos taurus OX=9913 GN=BACE1 PE=2 SV=1
JBrowse
Actinia equinaEGACTEQ4350003168-PAXP_031568918.1beta-secretase 1-like [Actinia tenebrosa]Q2HJ40
Beta-secretase 1 OS=Bos taurus OX=9913 GN=BACE1 PE=2 SV=1
JBrowse
Actinia equinaEGACTEQ4350038926-PAXP_031568918.1beta-secretase 1-like [Actinia tenebrosa]Q1KLR6
Beta-secretase 1 OS=Cavia porcellus OX=10141 GN=BACE1 PE=2 S
JBrowse
Actinia equinaEGACTEQ4350051105-PAXP_031568918.1beta-secretase 1-like [Actinia tenebrosa]Q2HJ40
Beta-secretase 1 OS=Bos taurus OX=9913 GN=BACE1 PE=2 SV=1
JBrowse
Acropora floridaaflo_s0047.g5.t1XP_044180741.1beta-secretase 1-like [Acropora millepora]Q2HJ40
Beta-secretase 1 OS=Bos taurus OX=9913 GN=BACE1 PE=2 SV=1
JBrowse
Acropora gemmiferaagem_s0005.g4.t1XP_044180741.1beta-secretase 1-like [Acropora millepora]Q2HJ40
Beta-secretase 1 OS=Bos taurus OX=9913 GN=BACE1 PE=2 SV=1
JBrowse
Acropora hemprichiiAhemp_013077-T1XP_044180741.1beta-secretase 1-like [Acropora millepora]Q2HJ40
Beta-secretase 1 OS=Bos taurus OX=9913 GN=BACE1 PE=2 SV=1
JBrowse
Acropora hyacinthusahya_s0001.g807.t1XP_044180741.1beta-secretase 1-like [Acropora millepora]Q2HJ40
Beta-secretase 1 OS=Bos taurus OX=9913 GN=BACE1 PE=2 SV=1
JBrowse
Alvinactis idsseensis sp. Nov.alvinactis_v1_g11917XP_031568918.1beta-secretase 1-like [Actinia tenebrosa]Q1KLR6
Beta-secretase 1 OS=Cavia porcellus OX=10141 GN=BACE1 PE=2 S
JBrowse
Alvinactis idsseensis sp. Nov.alvinactis_v1_g11922XP_020899216.1beta-secretase 1 [Exaiptasia diaphana]Q2HJ40
Beta-secretase 1 OS=Bos taurus OX=9913 GN=BACE1 PE=2 SV=1
JBrowse
Acropora intermediaaint_s0077.g88.t1XP_044180741.1beta-secretase 1-like [Acropora millepora]Q2HJ40
Beta-secretase 1 OS=Bos taurus OX=9913 GN=BACE1 PE=2 SV=1
JBrowse
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