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This orthogroup contains 205 genes from 143 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 205 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR46141 | SODIUM LEAK CHANNEL NON-SELECTIVE PROTEIN | 183 / 205 | 89.3% | 100.0% of 183 | ≥80% support |
| Pfam | PF00520 | Ion_trans — Ion transport protein | 177 / 205 | 86.3% | 100.0% of 177 | ≥80% support |
| GO | GO:0005261 Molecular Function | monoatomic cation channel activity | 183 / 205 | 89.3% | 100.0% of 183 | ≥80% support |
| GO | GO:0005886 Cellular Component | plasma membrane | 183 / 205 | 89.3% | 100.0% of 183 | ≥80% support |
| GO | GO:0032224 Biological Process | positive regulation of synaptic transmission, cholinergic | 183 / 205 | 89.3% | 100.0% of 183 | ≥80% support |
| GO | GO:0032230 Biological Process | positive regulation of synaptic transmission, GABAergic | 183 / 205 | 89.3% | 100.0% of 183 | ≥80% support |
| GO | GO:0005216 Molecular Function | monoatomic ion channel activity | 177 / 205 | 86.3% | 96.7% of 183 | ≥80% support |
| GO | GO:0006811 Biological Process | monoatomic ion transport | 177 / 205 | 86.3% | 96.7% of 183 | ≥80% support |
| GO | GO:0016020 Cellular Component | membrane | 177 / 205 | 86.3% | 96.7% of 183 | ≥80% support |
| GO | GO:0055085 Biological Process | transmembrane transport | 177 / 205 | 86.3% | 96.7% of 183 | ≥80% support |
| KEGG | K21863 | NALCN — Ion channels | 129 / 205 | 62.9% | 96.3% of 134 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Acropora acuminata | aacu_s0329.g24.t1 | XP_015755489.1 | PREDICTED: sodium leak channel non-selective protein-like [Acropora digitifera] | Q8IZF0 Sodium leak channel NALCN OS=Homo sapiens OX=9606 GN=NALCN P | JBrowse |
| Alatina alata | Aala_g609.t1 | XP_005989995.1 | PREDICTED: mitochondrial import inner membrane translocase subunit TIM44 [Latimeria chalumnae] | O35857 Mitochondrial import inner membrane translocase subunit TIM4 | JBrowse |
| Aurelia aurita | scaffold34.g37.t1 | none | – | JBrowse | |
| Aurelia aurita complex sp. Pacific | scaffold1.g41.t1 | none | – | JBrowse | |
| Acropora austera | ENSKKQP00000051716.1 | XP_029195821.2 | sodium leak channel non-selective protein-like [Acropora millepora] | Q8IZF0 Sodium leak channel NALCN OS=Homo sapiens OX=9606 GN=NALCN P | JBrowse |
| Acropora austera | ENSKKQP00000051722.1 | XP_029195821.2 | sodium leak channel non-selective protein-like [Acropora millepora] | Q8IZF0 Sodium leak channel NALCN OS=Homo sapiens OX=9606 GN=NALCN P | JBrowse |
| Acropora awi | aawi_s0195.g10.t1 | XP_029195821.2 | sodium leak channel non-selective protein-like [Acropora millepora] | Q8IZF0 Sodium leak channel NALCN OS=Homo sapiens OX=9606 GN=NALCN P | JBrowse |
| Acropora cervicornis | KAK2554613.1 | XP_029195821.2 | sodium leak channel non-selective protein-like [Acropora millepora] | Q8IZF0 Sodium leak channel NALCN OS=Homo sapiens OX=9606 GN=NALCN P | JBrowse |
| Aurelia coerulea | evm.model.ptg000031l.265 | XP_047127519.1 | sodium leak channel NALCN [Hydra vulgaris] | Q8IZF0 Sodium leak channel NALCN OS=Homo sapiens OX=9606 GN=NALCN P | JBrowse |
| Acropora cytherea | acyt_s0049.g23.t1 | XP_029195821.2 | sodium leak channel non-selective protein-like [Acropora millepora] | Q8IZF0 Sodium leak channel NALCN OS=Homo sapiens OX=9606 GN=NALCN P | JBrowse |
| Acropora digitifera | chr7Alt.g16450.t1 | none | – | JBrowse | |
| Acropora echinata | aech_s0005.g357.t1 | XP_029195821.2 | sodium leak channel non-selective protein-like [Acropora millepora] | Q8IZF0 Sodium leak channel NALCN OS=Homo sapiens OX=9606 GN=NALCN P | JBrowse |
| Actinia equina | EGACTEQ4350013834-PA | XP_031558376.1 | sodium leak channel non-selective protein-like [Actinia tenebrosa] | Q8IZF0 Sodium leak channel NALCN OS=Homo sapiens OX=9606 GN=NALCN P | JBrowse |
| Acropora florida | aflo_s0279.g10.t1 | XP_029195821.2 | sodium leak channel non-selective protein-like [Acropora millepora] | Q8IZF0 Sodium leak channel NALCN OS=Homo sapiens OX=9606 GN=NALCN P | JBrowse |
| Acropora florida | aflo_s3190.g1.t1 | XP_029195821.2 | sodium leak channel non-selective protein-like [Acropora millepora] | Q8IZF0 Sodium leak channel NALCN OS=Homo sapiens OX=9606 GN=NALCN P | JBrowse |
| Acropora gemmifera | agem_s0171.g31.t1 | XP_029195821.2 | sodium leak channel non-selective protein-like [Acropora millepora] | Q8IZF0 Sodium leak channel NALCN OS=Homo sapiens OX=9606 GN=NALCN P | JBrowse |
| Acropora hemprichii | Ahemp_011903-T1 | XP_029195821.2 | sodium leak channel non-selective protein-like [Acropora millepora] | Q8IZF0 Sodium leak channel NALCN OS=Homo sapiens OX=9606 GN=NALCN P | JBrowse |
| Acropora hyacinthus | ahya_s0050.g46.t1 | XP_029195821.2 | sodium leak channel non-selective protein-like [Acropora millepora] | Q8IZF0 Sodium leak channel NALCN OS=Homo sapiens OX=9606 GN=NALCN P | JBrowse |
| Alvinactis idsseensis sp. Nov. | alvinactis_v1_g21448 | XP_020895810.1 | sodium leak channel non-selective protein [Exaiptasia diaphana] | Q8IZF0 Sodium leak channel NALCN OS=Homo sapiens OX=9606 GN=NALCN P | JBrowse |
| Acropora intermedia | aint_s0572.g9.t1 | XP_029195821.2 | sodium leak channel non-selective protein-like [Acropora millepora] | Q8IZF0 Sodium leak channel NALCN OS=Homo sapiens OX=9606 GN=NALCN P | JBrowse |